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Global Medical Director Gastroenterology& Rare Disease

Alfasigma group
Mechelen
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Publish Date: Jun 19, 2026

Mechelen, BE

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Global Medical Director Gastroenterology\& Rare Disease

Alfasigma is a privately held global healthcare company founded over 75 years ago in Italy, where it remains headquartered today in Bologna and Milan. The Group operates in over 100 markets spanning Europe, North and South America, Asia, and Africa.

Over three years ago, we embarked on a transformative journey to become a truly global innovative healthcare company with a leading focus on Gastrointestinal (GI) health. We have experienced remarkable growth, nearly doubled our revenues, expanding geographically, and integrating several key acquisitions. We have also evolved our portfolio, expanded into rare and specialty segments, and strengthened our pipeline and people's capabilities.

But our journey is far from complete! In fact, this is just the beginning of a bold new chapter in Alfasigma's history. We are committed to advancing innovation and leveraging our deep expertise to provide better health and a better quality of life for patients and consumers worldwide and expand our reach across diverse markets.

Purpose of the Job

Within the Global Medical Affairs Team, the Medical Director Gastroenterology Rare Disease has a business\-critical role to drive the global Medical Affairs strategy and execute on the medical action plan in close partnership with the commercial and R\&D parts of the organization, supporting linerixibat.

Please note that this position can be based anywhere in the European Union and Switzerland.

Your role

Represent global medical affairs in the Global Brand Team, and be responsible for the development and execution of the medical strategy rare diseases

Act as internal expert on linerixibat in gastroenterology rare disease. Provide scientific advice to colleagues accordingly (e.g. medical training, regulatory affairs, business development)

Develop and advise on scientific content and strategy around products in development, pre\-launch, launch and in market\-related activities and materials

Be the medical lead for international congresses, including medical education

Lead medical advisory boards, and facilitate appropriate interpretation of insights and drive follow up of actions

Execute on scientific communication and training including key materials and alignment with countries

Demonstrate leadership in the process of data generation, interpretation and data display

Support with data generation needs, such as medical review of investigator\-initiated research proposals, real\-world data, registries, clinical studies, post\-hoc analyses, etc

Bring unsolicited grants through the grant approval process

Conduct and lead medical review and approval of materials

Lead or participate in globally focused meetings as needed to support the launch and in\-market success of Alfasigma products

Lead specific scientific projects to further advance understanding of the benefit: risk of linerixibat

Ensure the patient voice is embedded in activities from bench to bedside while working with the patient advocacy team

Advance understanding of the therapeutic landscape to identify opportunities for scientific leadership to meet patient needs

Align with the Head of the Global Medical Affairs Strategy Team to ensure that the execution of the medical activities are on track within the global brand strategy and within budget

Collaborate with Legal, Compliance and Regulatory to ensure proper and ethical interactions both with internal and external stakeholders

Ensure that developed materials and events are in compliance with with internal policies and external regulations

Who are you

A medical or scientific degree (Ph.D. or Pharm D) as a must

7\-10 years of experience in pharmaceutical industry, and skilled in working in cross\-functional matrix teams, including above country experience is required

Minimum 3\-5 years of experience in medical affairs in gastroenterology, including hepatology

Experience in the field of rare diseases is preferred

Experience in field\-based roles (e.g. Field Medical Director, Medical Science Liaison)

Experience in designing, planning, and executing on advisory boards, medical education at international symposia, internal medical communication as well as driving data generation and data display is required

Ability to develop and maintain strong relationships with experts within gastroenterology

Experience preparing global launches for products as well as launching a drug in country is strongly preferred

A genuine interest to advance science and healthcare in these areas to ultimately meet patient’s needs

Willingness to travel as needed for global collaboration

Why Join Alfasigma:

At Alfasigma, we foster a culture where the courage to innovate is key to our success.

We offer a competitive salary, comprehensive benefits, and extensive opportunities for professional growth and development.

Our commitment to people and patients is at the heart of everything we do. We value diversity and welcome individuals with unique perspectives and experiences. We believe that open\-mindedness, collaboration, and a shared passion for innovation are essential to achieving meaningful progress.

Join Alfasigma and become part of a forward\-thinking team dedicated to shaping the future of the pharmaceutical industry.

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