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via ats_greenhouse · 20 June 2026 ·4 days ago

Senior Manager, Clinical Operations - Cardiology

iterativehealth

Cambridge

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<div class="content-intro">
Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes.
 
We built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology. By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ambitions with high-performing research teams that expedite and expand access to novel therapeutics for patients in need. Today, Iterative Health is headquartered in Cambridge, Massachusetts, and New York City with 250+ employees world-wide.
</div>About Iterative Health 
At<a href="https://iterative.health/?utm_source=chatgpt.com"> Iterative Health</a>, we are transforming clinical research through the power of AI, technology, and human expertise. Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to improve patient outcomes. Through the Iterative Health Site Network — a premier network of 100+ clinical research sites across the US and Europe — we help expand and expedite access to novel therapeutics for patients in need.
 
Why This Role Matters
As the Senior Manager, Clinical Operations- Cardiology at Iterative Health you will serve as a strategic advisor to sponsors, CROs, and research sites, translating operational challenges into scalable solutions that improve study execution, accelerate activation timelines, and drive patient recruitment performance. By combining deep clinical research expertise with a consultative approach, this individual will help strengthen sponsor relationships, elevate site performance across the network, and contribute directly to Iterative Health's mission of bringing innovative therapies to patients faster.
As Iterative Health continues to expand its Site Network and partnerships with sponsors and CROs, operational excellence has become a critical differentiator. This role sits at the center of those relationships, helping ensure studies are launched efficiently, sites are set up for success, and sponsors receive the insights and partnership needed to achieve their clinical development goals. In particular, this role will own and scale the site activation process across the organization. This role is responsible for driving on-time site activations within SLAs, proactively identifying and resolving blockers, and improving activation workflows to increase speed, predictability, and efficiency.
This is a highly visible, customer-facing role with the opportunity to influence study strategy, shape operational best practices, and drive measurable impact across a growing portfolio of clinical trials.
 
Where You’ll Drive Impact 
Study Activation Ownership & Execution
<ul>
<li style="font-size: 10pt;">Own the end-to-end site activations, managing timelines, dependencies, and risks across multiple concurrent sites and trials</li>
<li style="font-size: 10pt;">Help teams prioritize tasks and ensure milestones are met within defined SLAs</li>
<li style="font-size: 10pt;">Maintain activation plans, status tracking, and documentation, escalating risks and delays proactively</li>
</ul>
<h3>Sponsor & CRO Partnership</h3>
<ul>
<li style="font-size: 10pt;">Serve as the primary operational partner to sponsors, CROs, and sites throughout the trial lifecycle</li>
<li style="font-size: 10pt;">Lead and support sponsor, CRO, and partner meetings by providing clinical operations expertise, actionable insights, and strategic recommendations.</li>
<li style="font-size: 10pt;">Build strong relationships with key stakeholders and ensure alignment on study goals, performance metrics, and operational priorities.</li>
<li style="font-size: 10pt;">Proactively communicate study risks, mitigation plans, and escalation strategies</li>
<li style="font-size: 10pt;">Facilitate educational sessions, webinars, and customer forums to strengthen engagement and share best practices.</li>
</ul>
<ul>
<li style="font-size: 10pt;">Travel as needed to customer sites, investigator meetings, conferences, and sponsor engagements (up to 30%).</li>
</ul>
 
<h3>Study Performance & Operational Excellence</h3>
<ul>
<li style="font-size: 10pt;">Monitor study performance metrics and own activation-specific reporting, including time-to-activation, SLA performance, and root causes of delays</li>
<li style="font-size: 10pt;">Build and maintain dashboards that provide clear stakeholder visibility</li>
<li style="font-size: 10pt;">Use data to inform prioritization, process improvements, and resourcing decisions</li>
<li style="font-size: 10pt;">Identify operational gaps affecting site activation, enrollment, and execution, and collaborate cross-functionally to address them</li>
<li style="font-size: 10pt;">Advocate for site needs and serve as a subject matter expert in clinical research operations</li>
<li style="font-size: 10pt;">Collaborate cross-functionally to implement solutions that improve site performance and study outcomes.</li>
<li style="font-size: 10pt;">Partner with sponsors and CROs to streamline processes and optimize site activation timelines.</li>
<li style="font-size: 10pt;">Performs related duties as requested </li>
</ul>
What You Bring to the Team 
<ul>
<li style="font-size: 10pt;">Bachelor's degree or equivalent combination of education and experience.</li>
<li style="font-size: 10pt;">8+ years of experience supporting Phase II-IV sponsor-funded clinical trials.</li>
<li style="font-size: 10pt;">Deep understanding of clinical trial operations, including study startup, feasibility, regulatory processes, protocol execution, and GCP requirements.</li>
<li style="font-size: 10pt;">Experience working directly with sponsors, CROs, investigative sites, and cross-functional stakeholders.</li>
<li style="font-size: 10pt;">Demonstrated ability to manage multiple priorities, navigate ambiguity, and drive projects to successful completion.</li>
<li style="font-size: 10pt;">Strong analytical, communication, and stakeholder management skills.</li>
<li style="font-size: 10pt;">Comfort adopting and leveraging new technologies and operational tools.</li>
<li style="font-size: 10pt;">Willingness to travel up to 30%.</li>
</ul>
<h3>Preferred Qualifications</h3>
<ul>
<li style="font-size: 10pt;">Experience in cardiology clinical research.</li>
<li style="font-size: 10pt;">Prior project or program management experience.</li>
<li style="font-size: 10pt;">5+ years of experience as a Clinical Research Associate (CRA) or Clinical Research Coordinator (CRC), or 3+ years leading clinical operations teams.</li>
<li style="font-size: 10pt;">Experience with CTMS platforms, with RealTime CTMS strongly preferred.</li>
<li style="font-size: 10pt;">Experience working in a high-growth or startup environment.</li>
<li style="font-size: 10pt;">Experience presenting to sponsors, CRO leadership, and executive stakeholders.</li>
</ul>
 
How We Work 
<ul>
<li style="font-size: 10pt;">Collaborative and low-ego team environment</li>
<li style="font-size: 10pt;">High ownership and accountability culture</li>
<li style="font-size: 10pt;">Fast-paced and highly iterative growth environment</li>
<li style="font-size: 10pt;">Open communication and continuous learning mindset</li>
<li style="font-size: 10pt;">Mission-driven organization focused on improving patient outcomes</li>
<li style="font-size: 10pt;">Comfor

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Senior Manager, Clinical Operations - Cardiology

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