Director, Pharmacometrics

Accountabilities:

• Lead and contribute to advanced pharmacometric modeling activities, including population PK, PK/PD, exposure-response, and model-based meta-analyses to support drug development decisions


• Apply quantitative methods such as disease modeling, trial simulation, dose optimization, and optimal study design to address complex clinical development questions


• Provide strategic input into drug development programs across multiple therapeutic areas, molecules, and stages of development


• Act as a scientific advisor to clients, supporting quantitative decision-making and enhancing development strategies through model-informed approaches


• Collaborate with cross-functional teams including scientists, consultants, and project stakeholders to deliver high-quality analytical outputs


• Conduct quality control and review of model code, datasets, and technical reports to ensure scientific rigor and compliance


• Contribute to internal methodological development, efficiency improvements, and innovation initiatives within the organization


• Potentially lead client engagements and support business development activities aligned with expertise and interests

Requirements

• PhD, MD, or PharmD in Pharmaceutical Sciences, Bioengineering, Pharmacology, Statistics, Applied Mathematics, Engineering, Medicine, or a related field


• 8–10 years of experience in pharmacometrics, clinical pharmacology, PK/PD modeling, or related quantitative disciplines


• Strong expertise in population PK, PK/PD, exposure-response modeling, and mechanistic or semi-mechanistic modeling approaches


• Proficiency in relevant tools and software such as NONMEM and R, along with strong statistical and programming capabilities


• Experience in clinical drug development, including trial design, execution, and regulatory support activities


• Proven ability to apply model-informed drug development approaches in both industry and consulting environments


• Strong analytical thinking, problem-solving skills, and ability to translate complex data into actionable insights


• Excellent communication and stakeholder management skills, with the ability to operate in multidisciplinary and client-facing settings


• Experience in consulting or cross-company project environments is highly desirable

• Opportunity to work on high-impact global drug development programs across multiple therapeutic areas


• Strong exposure to advanced model-informed drug development methodologies and cutting-edge scientific approaches


• Collaborative, expert-driven environment with access to senior scientists and multidisciplinary teams


• Flexible working arrangements and international exposure


• Continuous learning opportunities and support for scientific and professional development


• Possibility to lead initiatives in methodology, innovation, and operational excellence


• Competitive compensation and comprehensive benefits package including healthcare and social protections

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